| First Author | Kishi T | Year | 1997 |
| Journal | Biochem Biophys Res Commun | Volume | 232 |
| Issue | 1 | Pages | 5-9 |
| PubMed ID | 9125150 | Mgi Jnum | J:38935 |
| Mgi Id | MGI:86321 | Doi | 10.1006/bbrc.1997.6218 |
| Citation | Kishi T, et al. (1997) Molecular cloning of human GRB-7 co-amplified with CAB1 and c-ERBB-2 in primary gastric cancer. Biochem Biophys Res Commun 232(1):5-9 |
| abstractText | Many amplified-chromosome regions in human cancers have been identified, while there are only a limited number of reports for amplified genes in a single amplicon. We recently isolated four cDNA clones, A39, B47, C51, and CAB1, from 500 kilobases of yeast artificial chromosome DNA containing the c-ERBB-2 gene. B47 consisted of 615 base pairs and had about 85% homology with the corresponding sequence of mouse Grb-7. We report here the structure of human GRB-7 cDNA, and we report that the amounts of mRNA for c-ERBB-2, CAB1, and GRB-7 were elevated in concordance with the amplification. |
