First Author | Reed JC | Year | 1997 |
Journal | Nature | Volume | 387 |
Issue | 6635 | Pages | 773-6 |
PubMed ID | 9194558 | Mgi Jnum | J:41230 |
Mgi Id | MGI:893309 | Doi | 10.1038/42867 |
Citation | Reed JC (1997) Double identity for proteins of the Bcl-2 family. Nature 387(6635):773-6 |
abstractText | Bcl-2 is an oncogenic protein that acts by inhibiting programmed cell death. The mechanisms used by this and related anti-apoptotic proteins to protect cells from cytotoxic stimuli are now emerging, with the discovery that Bcl-2 can function both as an ion channel and as an adaptor or docking protein. |