| First Author | Kumar S | Year | 1997 |
| Journal | Leukemia | Volume | 11 Suppl 3 |
| Pages | 385-6 | PubMed ID | 9209399 |
| Mgi Jnum | J:41262 | Mgi Id | MGI:893341 |
| Citation | Kumar S, et al. (1997) Characterization of a mammalian cell death gene Nedd2. Leukemia 11 Suppl 3:385-6 |
| abstractText | Through subtraction cloning approach, we have identified a set of mouse genes with developmentally down-regulated expression in brain. One such gene, termed Nedd2, was found to encode protein similar to the mammalian interleukin-1b-converting enzyme (ICE) and the product of the nematode (C. elegans) cell death gene ced-3. Our data suggest that Nedd2 is an important component of the mammalian programmed cell death machinery. |
