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Publication : The genetics of obesity.

First Author  Naggert J Year  1997
Journal  Curr Opin Genet Dev Volume  7
Issue  3 Pages  398-404
PubMed ID  9229117 Mgi Jnum  J:41474
Mgi Id  MGI:893952 Doi  10.1016/s0959-437x(97)80155-4
Citation  Naggert J, et al. (1997) The genetics of obesity. Curr Opin Genet Dev 7(3):398-404
abstractText  Despite the influence of obesity in predisposing to many diseases, and evidence for high heritability, efforts to identify human genes with major effects on bodyweight have not yet been successful. In contrast, remarkable progress has been made in the identification and characterization of the genes mutated in five monogenic mouse models of obesity. These genes have led to new insights into the etiology of obesity and provide promising targets for therapeutic intervention.
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