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Publication : NO synthase-II is transiently expressed in embryonic mouse olfactory receptor neurons.

First Author  Arnhold S Year  1997
Journal  Neurosci Lett Volume  229
Issue  3 Pages  165-8
PubMed ID  9237484 Mgi Jnum  J:42234
Mgi Id  MGI:1095372 Doi  10.1016/s0304-3940(97)00457-6
Citation  Arnhold S, et al. (1997) NO synthase-II is transiently expressed in embryonic mouse olfactory receptor neurons. Neurosci Lett 229(3):165-8
abstractText  Among three NO synthase (NOS) isoforms only the inducible NOS-II was localized in developing olfactory receptor neurons of the mouse. First NOS-II immunoreactive receptor cells including their processes were detected by embryonic day 11 when the olfactory pit starts to invaginate. Cellular staining lasted until embryonic day 16, and was reduced during the next few days. At embryonic day 20 no reactivity was found in the olfactory epithelium, whereas centripetal nerve fibers remained positive. This transient expression of NOS-II implies a role for the differentiation of early olfactory receptor neurons and synaptic plasticity.
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