| First Author | Durkin ME | Year | 1997 |
| Journal | FEBS Lett | Volume | 411 |
| Issue | 2-3 | Pages | 296-300 |
| PubMed ID | 9271224 | Mgi Jnum | J:42132 |
| Mgi Id | MGI:1095218 | Doi | 10.1016/s0014-5793(97)00686-8 |
| Citation | Durkin ME, et al. (1997) Tissue-specific expression of the human laminin alpha5-chain, and mapping of the gene to human chromosome 20q13.2-13.3 and to distal mouse chromosome 2 near the locus for the ragged (Ra) mutation. FEBS Lett 411(2-3):296-300 |
| abstractText | To investigate the function of the laminin alpha5-chain, previously identified in mice, cDNA clones encoding the 953-amino-acid carboxy terminal G-domain of the human laminin alpha5-chain were characterized. Northern blot analysis showed that the laminin alpha5-chain is expressed in human placenta, heart, lung, skeletal muscle, kidney, and pancreas. The human laminin alpha5-chain gene (LAMA5) was assigned to chromosome 20q13.2-q13.3 by in situ hybridization, and the mouse gene (Lama5) was mapped by linkage analysis to a syntonic region of distal chromosome 2, close to the locus for the ragged (Ra) mutation. |
