First Author | Ganesh S | Year | 1997 |
Journal | Gene | Volume | 196 |
Issue | 1-2 | Pages | 287-90 |
PubMed ID | 9322768 | Mgi Jnum | J:42944 |
Mgi Id | MGI:1096766 | Doi | 10.1016/s0378-1119(97)00241-2 |
Citation | Ganesh S, et al. (1997) CvSox-4, the lizard homologue of the human SOX4 gene, shows remarkable conservation among the amniotes. Gene 196(1-2):287-90 |
abstractText | SOX family genes share a high sequence similarity with the HMG box region of the human Y chromosomal gene, SRY. We have cloned and sequenced the HMG box motif of a Sox gene of the lizard, Calotes versicolor. A database search for the cloned sequence, CvSox-4, revealed 100% identity with the SOX4 gene of the human and its homologue in a bird. The result strongly suggests that SOX4 evolved prior to the diversification of amniotes and is highly conserved. |