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Publication : CvSox-4, the lizard homologue of the human SOX4 gene, shows remarkable conservation among the amniotes.

First Author  Ganesh S Year  1997
Journal  Gene Volume  196
Issue  1-2 Pages  287-90
PubMed ID  9322768 Mgi Jnum  J:42944
Mgi Id  MGI:1096766 Doi  10.1016/s0378-1119(97)00241-2
Citation  Ganesh S, et al. (1997) CvSox-4, the lizard homologue of the human SOX4 gene, shows remarkable conservation among the amniotes. Gene 196(1-2):287-90
abstractText  SOX family genes share a high sequence similarity with the HMG box region of the human Y chromosomal gene, SRY. We have cloned and sequenced the HMG box motif of a Sox gene of the lizard, Calotes versicolor. A database search for the cloned sequence, CvSox-4, revealed 100% identity with the SOX4 gene of the human and its homologue in a bird. The result strongly suggests that SOX4 evolved prior to the diversification of amniotes and is highly conserved.
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