| First Author | Rosengren E | Year | 1997 |
| Journal | FEBS Lett | Volume | 417 |
| Issue | 1 | Pages | 85-8 |
| PubMed ID | 9395080 | Mgi Jnum | J:44506 |
| Mgi Id | MGI:1100390 | Doi | 10.1016/s0014-5793(97)01261-1 |
| Citation | Rosengren E, et al. (1997) The macrophage migration inhibitory factor MIF is a phenylpyruvate tautomerase. FEBS Lett 417(1):85-8 |
| abstractText | A macrophage migration inhibitory factor (MIF), originally described as a product of activated lymphocytes, has been defined as a 12 kDa protein, expressed in a wide variety of tissues. Here MIF is identified as a phenylpyruvate tautomerase (EC 5.3.2.1) having p-hydroxyphenylpyruvate and phenylpyruvate as its natural substrates. The definition of MIF as an enzyme may yield insight into the mechanism of action of this proinflammatory and immunomodulating cytokine. |
