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Publication : Cloning of a novel Y-box homology protein (chkYB-1HP) cDNA lacking the cold-shock domain.

First Author  Nambiar A Year  1998
Journal  Biochim Biophys Acta Volume  1395
Issue  1 Pages  1-6
PubMed ID  9434143 Mgi Jnum  J:44886
Mgi Id  MGI:1101432 Doi  10.1016/s0167-4781(97)00141-3
Citation  Nambiar A, et al. (1998) Cloning of a novel Y-box homology protein (chkYB-1HP) cDNA lacking the cold-shock domain. Biochim Biophys Acta 1395(1):1-6
abstractText  We have isolated the complete cDNA clone of a novel 262 amino acid Chicken YB-1 Homology Protein (chkYB-1HP) by screening a chicken embryo cDNA expression library. While the chkYB-1HP is identical over its carboxyl-terminal 78 amino acids with the Y-box protein YB-1, it differs strikingly from all other Y-box transcription factors by lacking the cold-shock domain (CSD). We propose that proteins like chkYB-1HP that lack the CSD, but retain the hydrophilic carboxyl domain could regulate Y-box proteins through the formation of heterodimeric complexes.
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