| First Author | Korver W | Year | 1997 |
| Journal | Genomics | Volume | 46 |
| Issue | 3 | Pages | 435-42 |
| PubMed ID | 9441747 | Mgi Jnum | J:45565 |
| Mgi Id | MGI:1195616 | Doi | 10.1006/geno.1997.5065 |
| Citation | Korver W, et al. (1997) The human TRIDENT/HFH-11/FKHL16 gene: structure, localization, and promoter characterization. Genomics 46(3):435-42 |
| abstractText | We recently identified the winged-helix/fork head transcription factor Trident in mouse and described its expression in cycling cells. Here we report the isolation and characterization of the human TRIDENT (HGMW-approved symbol FKHL16) cDNA and gene. Homology between the human and the mouse Trident proteins was 79%. The gene consists of 10 exons and is located on chromosome 12 band p13. The winged-helix DNA-binding domain is encoded on three exons. Analysis of the promoter in synchronized Rat-1 fibroblasts revealed a fragment of 300 bases responsible for the cell cycle-specific expression of the TRIDENT gene. |
