| First Author | Telford EA | Year | 1998 |
| Journal | Biochem Biophys Res Commun | Volume | 242 |
| Issue | 2 | Pages | 407-12 |
| PubMed ID | 9446808 | Mgi Jnum | J:45396 |
| Mgi Id | MGI:1195368 | Doi | 10.1006/bbrc.1997.7977 |
| Citation | Telford EA, et al. (1998) cDNA cloning, genomic organization, and chromosomal localization of a novel human gene that encodes a kinesin-related protein highly similar to mouse Kif3C. Biochem Biophys Res Commun 242(2):407-12 |
| abstractText | We report the cloning and characterization of a novel human kinesin-like gene with strong homology to the mouse kinesin Kif3c. The full-length cDNA contains an open reading frame of 2382 nucleotides encoding a predicted 793 amino acid peptide that includes a 389 amino acid motor domain conserved among other kinesins. PCR and DNA sequence analysis of PAC clones containing the human KIF3C sequence revealed that the gene contains 8 exons. All introns have the conserved GT and AG dinucleotides present at their donor and acceptor sites, respectively. We have localized KIF3C to chromosome band 2p23 by fluorescence in situ hybridization. |
