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Publication : Expression analysis and chromosomal mapping of a novel human gene, APRIL, encoding an acidic protein rich in leucines.

First Author  Mencinger M Year  1998
Journal  Biochim Biophys Acta Volume  1395
Issue  2 Pages  176-80
PubMed ID  9473664 Mgi Jnum  J:46301
Mgi Id  MGI:1197539 Doi  10.1016/s0167-4781(97)00165-6
Citation  Mencinger M, et al. (1998) Expression analysis and chromosomal mapping of a novel human gene, APRIL, encoding an acidic protein rich in leucines. Biochim Biophys Acta 1395(2):176-80
abstractText  Clone 120041 was selected from the EST database for sequence similarity to DEK and SET proteins rearranged in leukemias. The ends of the cDNA were isolated by RACE technique. The assembled cDNA encodes an LRR-containing protein of 251 amino acids designated APRIL (acidic protein rich in leucines). APRIL has high similarity to human pp32, also named PHAPI (bovine I[PP2A]1), and to rat LANP, respectively. APRIL shows tissue-specific expression as shown by Northern blot analysis. It was localized to 15q25 by FISH.
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