| First Author | Anderson GJ | Year | 1998 |
| Journal | Genomics | Volume | 48 |
| Issue | 1 | Pages | 34-9 |
| PubMed ID | 9503013 | Mgi Jnum | J:43668 |
| Mgi Id | MGI:1098302 | Doi | 10.1006/geno.1997.5138 |
| Citation | Anderson GJ, et al. (1998) Mapping the gene for sex-linked anemia: an inherited defect of intestinal iron absorption in the mouse. Genomics 48(1):34-9 |
| abstractText | The sex-linked anemic (sla) mouse carries an anemia that results from an inherited defect of intestinal iron absorption and provides an ideal model with which to investigate this poorly understood yet clinically important process. We have precisely mapped the sla locus within the central region of the X chromosome in relation to a panel of microsatellite markers. Analysis of over 500 progeny from an intraspecific intercross and a smaller intraspecific backcross segregating sla established the following locus order in the sla region: DXMit45-sla- (DXMit16, DXMit96)-DXMit41-DXMit169-DXMit170-DXMit148- (DXMit18, DXMit171)-DXMit84-DXMit64. The two microsatellites DXMit16 and DXMit96 are located 0.60 +/- 0.35cM from sla and form the telomeric limit of the sla region. The mapping of the sla locus is an important first step to identifying the gene itself. (C) 1998 Academic Press. |
