| First Author | Nakazato S | Year | 1998 |
| Journal | Genomics | Volume | 48 |
| Issue | 3 | Pages | 363-8 |
| PubMed ID | 9545642 | Mgi Jnum | J:46822 |
| Mgi Id | MGI:1202116 | Doi | 10.1006/geno.1997.5178 |
| Citation | Nakazato S, et al. (1998) Physical linkage of the B29/Ig-beta (CD79B) gene to the skeletal muscle, sodium-channel, and growth hormone genes in rat and human. Genomics 48(3):363-8 |
| abstractText | In the region between the polyadenylation site of the rat skeletal muscle (SkM) Na-channel gene and the 5' end of the growth hormone (GH) gene, a gene coding for B-cell- specific membrane protein B29/Ig-beta was found and noted to have the same orientation as the Na-channel and GH genes. Rat B29/Ig-beta gene was 3.1 kb in length with six exons and was separated by 3.3 and 9.3 kb from Na-channel and GH genes, respectively. Rat B29/Ig-beta protein comprised 228 amino acids, and its amino acid sequence was 85 and 69% identical with the mouse and human counterparts, respectively, With the long-area PCR method, genomic DNA connecting human SkM Na-channel (SCN4A) and B29/Ig-beta (CD79B) genes and CD79B and GH (Grill) genes was amplified, and the physical linkage of SCN4A/CD79B/GH1 genes in the human genome was established. The human CD79B gene was separated by 6.3 and 10.5 kb from the SCN4A and GH1 genes, respectively. (C) 1998 Academic Press. |
