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Publication : Cloning of chicken and mouse alpha 1b adrenergic receptor.

First Author  Alonso-Llamazares A Year  1998
Journal  Biochim Biophys Acta Volume  1396
Issue  3 Pages  263-6
PubMed ID  9545578 Mgi Jnum  J:46541
Mgi Id  MGI:1201290 Doi  10.1016/s0167-4781(97)00230-3
Citation  Alonso-Llamazares A, et al. (1998) Cloning of chicken and mouse alpha 1b adrenergic receptor. Biochim Biophys Acta 1396(3):263-6
abstractText  A partial cDNA encoding most of the third intracellular loop of the chicken alpha 1b adrenergic receptor subtype, obtained by reverse transcription-polymerase chain reaction (RT-PCR) techniques using degenerate primers derived from mammalian sequences, was used to isolate an alpha 1b adrenergic receptor cDNA from brain. The cDNA encodes a potential protein of 507 amino acids and Northern hybridization of poly(A)+ RNA from chicken brain of different developmental stages detected a single 3.5 kb transcript. Analysis of receptor expression indicated that the alpha 1b adrenergic receptor is widely distributed in chicken tissues, specially kidney and liver. cDNA and genomic clones encoding sequences of the mouse alpha 1b adrenergic receptor were also isolated.
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