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Publication : Development of laminar distributions of kainate receptors in the somatosensory cortex of mice.

First Author  Jabłońska B Year  1998
Journal  Brain Res Volume  791
Issue  1-2 Pages  325-9
PubMed ID  9593973 Mgi Jnum  J:47717
Mgi Id  MGI:1205957 Doi  10.1016/s0006-8993(98)00200-5
Citation  Jablonska B, et al. (1998) Development of laminar distributions of kainate receptors in the somatosensory cortex of mice. Brain Res 791(1-2):325-9
abstractText  Kainate receptors were present at birth in the murine somatosensory cortex as revealed by quantitative in vitro autoradiography. During the first five postnatal days [3H]kainate binding rapidly increased and the maximum density in layer IV was reached at P12. The adult laminar pattern of receptor binding distribution was established by the third postnatal week with the heaviest labeling of infragranular layers. The sharp increase of kainate receptor during the first postnatal week coincides with the critical period for cytoarchitectonic plasticity of the barrels and establishment of functional thalamo-cortical connections in the barrel field. Copyright 1998 Elsevier Science B.V.
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