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Publication : Analysis of Peg1/Mest imprinting in the mouse.

First Author  Reule M Year  1998
Journal  Dev Genes Evol Volume  208
Issue  3 Pages  161-3
PubMed ID  9601990 Mgi Jnum  J:48293
Mgi Id  MGI:1267143 Doi  10.1007/s004270050168
Citation  Reule M, et al. (1998) Analysis of Peg1/Mest imprinting in the mouse. Dev Genes Evol 208(3):161-3
abstractText  In the mouse, Peg1/Mest is widely expressed in mesoderm-derived tissues. In separate studies, it has been shown to be maternally imprinted, that is, only the paternally inherited allele is active in mice and in humans. Here, we provide evidence that Peg1/Mest is expressed at very low levels in all tissues of adult mice as assessed by RT-PCR. Moreover, by using species-specific polymorphisms in the Peg1/Mest sequence we can demonstrate that in adult mice the gene remains imprinted in all of these tissues.
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