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Publication : Comparative FISH-mapping of the prion protein gene (PRNP) on cattle, river buffalo, sheep and goat chromosomes.

First Author  Iannuzzi L Year  1998
Journal  Cytogenet Cell Genet Volume  81
Issue  3-4 Pages  202-4
PubMed ID  9730603 Mgi Jnum  J:49776
Mgi Id  MGI:1278109 Doi  10.1159/000015030
Citation  Iannuzzi L, et al. (1998) Comparative FISH-mapping of the prion protein gene (PRNP) on cattle, river buffalo, sheep and goat chromosomes. Cytogenet Cell Genet 81(3-4):202-4
abstractText  Comparative FISH-mapping of the prion protein gene (PRNP) was performed on cattle (BTA), river buffalo (BBU), sheep (OAR) and goat (CHI) chromosomes using a PCR-product as a probe and R-banding. PRNP was mapped to BTA13q17, BBU14q15, OAR13q15 and CHI13q15 according to standard nomenclatures. These chromosomes and bands were homoeologous among the four species, confirming the high degree of gene and chromosome banding conservation among bovids. Furthermore, the assignment of PRNP to river buffalo and goat chromosomes allowed us to indirectly assign the bovine syntenic group U11 to specific chromosomes, since it is the first in situ localization on BBU14 and CHI13.
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