First Author | Kuroiwa A | Year | 1998 |
Journal | Cytogenet Cell Genet | Volume | 81 |
Issue | 3-4 | Pages | 208-12 |
PubMed ID | 9730605 | Mgi Jnum | J:49742 |
Mgi Id | MGI:1278074 | Doi | 10.1159/000015032 |
Citation | Kuroiwa A, et al. (1998) Comparative FISH mapping of mouse and rat homologues of twenty-five human X-linked genes. Cytogenet Cell Genet 81(3-4):208-12 |
abstractText | We constructed a comparative cytogenetic map of 25 functional genes in mouse and rat X chromosomes by direct R-banding fluorescence in situ hybridization. Nineteen and 22 out of the 25 genes, which have been mapped on the human X chromosome, were newly localized to mouse and rat X chromosomes, respectively. Twenty-two additional genes were integrated in the rat-mouse-human comparative map of the X chromosome in this study. Comparison of the gene order indicated the presence of four chromosome segments with conserved linkage homology between mouse and rat X chromosomes, suggesting that a minimum of four chromosomal inversion events occurred between mouse and rat X chromosomes during the evolution of the two species. Four chromosome segments with conserved linkage homology were found between human and rat X chromosomes. |