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Publication : Expression of aromatase in the embryonic and postnatal mouse striatum.

First Author  Küppers E Year  1998
Journal  Brain Res Mol Brain Res Volume  63
Issue  1 Pages  184-8
PubMed ID  9838103 Mgi Jnum  J:51551
Mgi Id  MGI:1316895 Doi  10.1016/s0169-328x(98)00279-4
Citation  Kuppers E, et al. (1998) Expression of aromatase in the embryonic and postnatal mouse striatum. Brain Res Mol Brain Res 63(1):184-8
abstractText  Estrogen influences striatal activity and the development of the nigrostriatal system. This study is concerned with the ontogenetic and postnatal expression of aromatase in the mouse striatum. Aromatase activity and mRNA expression were detectable in the embryonic striatum and increased postnatally with no differences between sexes. Aromatase-positive cells were uniformly distributed within the striatum. These data demonstrate that estrogen formation is an intrinsic property of striatal cells and suggest that estrogen may be important for striatal development and function. Copyright 1998 Elsevier Science B.V.
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