| First Author | Wegner M | Year | 1999 |
| Journal | Nucleic Acids Res | Volume | 27 |
| Issue | 6 | Pages | 1409-20 |
| PubMed ID | 10037800 | Mgi Jnum | J:53989 |
| Mgi Id | MGI:1333715 | Doi | 10.1093/nar/27.6.1409 |
| Citation | Wegner M (1999) From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res 27(6):1409-20 |
| abstractText | Sox proteins belong to the HMG box superfamily of DNA-binding proteins and are found throughout the animal kingdom. They are involved in the regulation of such diverse developmental processes as germ layer formation, organ development and cell type specifi-cation. Hence, deletion or mutation of Sox proteins often results in developmental defects and congenital disease in humans. Sox proteins perform their function in a complex interplay with other transcription factors in a manner highly dependent on cell type and promoter context. They exhibit a remarkable crosstalk and functional redundancy among each other. |
