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Publication : Lung surfactant proteins involved in innate immunity.

First Author  Eggleton P Year  1999
Journal  Curr Opin Immunol Volume  11
Issue  1 Pages  28-33
PubMed ID  10047533 Mgi Jnum  J:53150
Mgi Id  MGI:1331335 Doi  10.1016/s0952-7915(99)80006-5
Citation  Eggleton P, et al. (1999) Lung surfactant proteins involved in innate immunity. Curr Opin Immunol 11(1):28-33
abstractText  The two lung surfactant collectins, surfactant protein (SP)-A and SP-D, are involved in host defence against infectious and allergenic agents via enhancement of killing and clearance by macrophages and neutrophils. Recent gene-knockout, protein engineering and physiological studies have emphasised the roles that SP-A and SP-D play in acute inflammatory responses.
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