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Publication : Multiple gamma c-dependent cytokines regulate T-cell development.

First Author  Malek TR Year  1999
Journal  Immunol Today Volume  20
Issue  2 Pages  71-6
PubMed ID  10098325 Mgi Jnum  J:53159
Mgi Id  MGI:1331344 Doi  10.1016/s0167-5699(98)01391-7
Citation  Malek TR, et al. (1999) Multiple gamma c-dependent cytokines regulate T-cell development. Immunol Today 20(2):71-6
abstractText  Mutations in the common gamma chain (gamma c) of cytokine receptors account for human X-linked severe combined immunodeficiency disease. gamma c contributes to ligand binding and signaling as a component of five cytokine receptors: interleukin-2-receptor (IL-2R), IL-4R, IL-7R, IL-9R and IL-15R. Here, Thomas Malek and colleagues discuss the contribution of individual gamma c-dependent cytokines in both conventional and intraepithelial T-cell development.
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