First Author | Malek TR | Year | 1999 |
Journal | Immunol Today | Volume | 20 |
Issue | 2 | Pages | 71-6 |
PubMed ID | 10098325 | Mgi Jnum | J:53159 |
Mgi Id | MGI:1331344 | Doi | 10.1016/s0167-5699(98)01391-7 |
Citation | Malek TR, et al. (1999) Multiple gamma c-dependent cytokines regulate T-cell development. Immunol Today 20(2):71-6 |
abstractText | Mutations in the common gamma chain (gamma c) of cytokine receptors account for human X-linked severe combined immunodeficiency disease. gamma c contributes to ligand binding and signaling as a component of five cytokine receptors: interleukin-2-receptor (IL-2R), IL-4R, IL-7R, IL-9R and IL-15R. Here, Thomas Malek and colleagues discuss the contribution of individual gamma c-dependent cytokines in both conventional and intraepithelial T-cell development. |