| First Author | Sakaguchi AY | Year | 1998 |
| Journal | Somat Cell Mol Genet | Volume | 24 |
| Issue | 3 | Pages | 157-63 |
| PubMed ID | 10226653 | Mgi Jnum | J:54708 |
| Mgi Id | MGI:1335730 | Doi | 10.1023/b:scam.0000007118.47691.d7 |
| Citation | Sakaguchi AY, et al. (1998) Chromosomal sublocalization of the transcribed human telomere repeat binding factor 2 gene and comparative mapping in the mouse. Somat Cell Mol Genet 24(3):157-63 |
| abstractText | Telomere repeat binding factor 2 (TERF2) is one of two recently cloned mammalian telomere binding protein genes. TERF2 binds as a dimer with high affinity to the double- stranded TTAGGG telomeric repent through an evolutionarily conserved myb-type DNA binding domain. TERF2 prevents telomere end-to-end-fusion and may be important in. Maintaining genomic stability. We localized the transcribed TERF2 gene to human chromosome 16q22.1, tightly linked to the EST HUM000S343. The mouse Terf2 gene is situated by itself in a newly defined ''bin'' on chromosome 8 one crossover distal to Psm 10 and Sntb2, Human TERF2 and mouse Terf2 are therefore part of a large evolutionarily conserved linkage group comprised of at feast 25 known paralogous genes between human chromosome 16q and mouse chromosome 8. |
