| First Author | Ikemoto K | Year | 1999 |
| Journal | Neurosci Lett | Volume | 271 |
| Issue | 1 | Pages | 53-6 |
| PubMed ID | 10471212 | Mgi Jnum | J:57438 |
| Mgi Id | MGI:1344581 | Doi | 10.1016/s0304-3940(99)00512-1 |
| Citation | Ikemoto K, et al. (1999) Cholinergic neurons with monoamine oxidase type B (MAOB)-activity in the laterodorsal tegmental nucleus of the mouse. Neurosci Lett 271(1):53-6 |
| abstractText | No neurons in the laterodorsal tegmental nucleus (LDTg) show monoamine oxidase (MAO) activity in the rat or monkey. However, in our recent study, many LDTg neurons with MAO type B (MAOB)-activity were found in MAOA-deficient mice that were derived from C3H mouse line. In the present study, LDTg neurons with MAOB-activity were found not only in normal C3H mouse but also in BALB/C and C57BL/6 mouse lines: MAO histochemistry revealed LDTg neurons with MAO-activity even after pharmacological suppression of MAOA-activity with clorgyline, a specific MAOA inhibitor, but not after pharmacological suppression of MAOB-activity with deprenyl, a specific MAOB inhibitor. LDTg neurons with MAOB-activity also showed NADPH-diaphorase-activity, a marker of cholinergic neurons. |
