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Publication : Expression pattern of the Tbr2 (Eomesodermin) gene during mouse and chick brain development.

First Author  Bulfone A Year  1999
Journal  Mech Dev Volume  84
Issue  1-2 Pages  133-8
PubMed ID  10473127 Mgi Jnum  J:55094
Mgi Id  MGI:1339661 Doi  10.1016/s0925-4773(99)00053-2
Citation  Bulfone A, et al. (1999) Expression pattern of the Tbr2 (Eomesodermin) gene during mouse and chick brain development. Mech Dev 84(1-2):133-8
abstractText  The members of the T-box gene family share a highly conserved DNA binding domain named the T-domain, and important developmental functions. Here we report the cloning of chicken Tbr1 and of murine and chicken Tbr2 (orthologs of the Xenopus eomesodermin gene), the mapping of the murine Tbr2 to chromosome 9, and their pattern of expression during mouse and chick embryogenesis. Both Tbr 1 and 2 have a restricted and conserved domain of expression in the telencephalic pallium of the two species. Chick Tbr2 has a specific and dynamic expression in the gastrulating embryo.
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