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Publication : Differential expression of Tbx4 and Tbx5 in Zebrafish fin buds.

First Author  Tamura K Year  1999
Journal  Mech Dev Volume  87
Issue  1-2 Pages  181-4
PubMed ID  10495283 Mgi Jnum  J:57827
Mgi Id  MGI:1345855 Doi  10.1016/s0925-4773(99)00126-4
Citation  Tamura K, et al. (1999) Differential expression of tbx4 and tbx5 in zebrafish fin buds. Mech Dev 87(1-2):181-4
abstractText  In here we report the identification of two new members of the T-box gene family, zf-tbx5 and zf-tbx4, from the Zebrafish, Danio rerio. The amino acid sequences within the T-box domain share high homology with the mouse, chick, and newt orthologs. Whole mount in situ hybridization revealed specific expression of these genes in the eye and Fin buds. zf-tbx5 expression is restricted to the pectoral Fin bud, whilst zf-tbx4 transcripts are confined in the pelvic Fin bud. These results reveal the conserved expression pattern of Tbx5 and Tbx4 during appendage development in all animal species studied to date.
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