| First Author | Davis ES | Year | 2002 |
| Journal | Genetics | Volume | 160 |
| Issue | 2 | Pages | 805-13 |
| PubMed ID | 11861581 | Mgi Jnum | J:75036 |
| Mgi Id | MGI:2159572 | Doi | 10.1093/genetics/160.2.805 |
| Citation | Davis ES, et al. (2002) Multiple Subunits of the Caenorhabditis elegans Anaphase-Promoting Complex Are Required for Chromosome Segregation During Meiosis I. Genetics 160(2):805-13 |
| abstractText | Two genes, originally identified in genetic screens for Caenorhabditis elegans mutants that arrest in metaphase of meiosis I, prove to encode subunits of the anaphase-promoting complex or cyclosome (APC/C). RNA interference studies reveal that these and other APC/C subunits are essential for the segregation of chromosomal homologs during meiosis I. Further, chromosome segregation during meiosis I requires APC/C functions in addition to the release of sister chromatid cohesion. |
