First Author | Roth DB | Year | 2002 |
Journal | Mol Cell | Volume | 10 |
Issue | 1 | Pages | 1-2 |
PubMed ID | 12150897 | Mgi Jnum | J:78520 |
Mgi Id | MGI:2384700 | Doi | 10.1016/s1097-2765(02)00573-7 |
Citation | Roth DB (2002) Amplifying mechanisms of lymphomagenesis. Mol Cell 10(1):1-2 |
abstractText | Mice doubly deficient for either XRCC4 or DNA ligase IV and p53 invariably develop lymphomas bearing characteristic chromosome translocations with gene amplification. A recent study highlights the importance of nonclassical end joining mechanisms in the formation of these oncogenic DNA rearrangements. |