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Publication : Amplifying mechanisms of lymphomagenesis.

First Author  Roth DB Year  2002
Journal  Mol Cell Volume  10
Issue  1 Pages  1-2
PubMed ID  12150897 Mgi Jnum  J:78520
Mgi Id  MGI:2384700 Doi  10.1016/s1097-2765(02)00573-7
Citation  Roth DB (2002) Amplifying mechanisms of lymphomagenesis. Mol Cell 10(1):1-2
abstractText  Mice doubly deficient for either XRCC4 or DNA ligase IV and p53 invariably develop lymphomas bearing characteristic chromosome translocations with gene amplification. A recent study highlights the importance of nonclassical end joining mechanisms in the formation of these oncogenic DNA rearrangements.
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