| First Author | Götze D | Year | 1980 |
| Journal | J Immunol | Volume | 124 |
| Issue | 6 | Pages | 2675-81 |
| PubMed ID | 6154735 | Mgi Jnum | J:78473 |
| Mgi Id | MGI:2384491 | Doi | 10.4049/jimmunol.124.6.2675 |
| Citation | Gotze D, et al. (1980) Histocompatibility-2 system in wild mice. X. Frequencies of H-2 and Ia antigens in wild mice from Europe and Africa. J Immunol 124(6):2675-81 |
| abstractText | In this study, data are presented on serologic H-2 typing of 320 wild mice collected in several parts of Europe and Egypt. The sample was typed for 39 class I (K, D) and 16 class II (Ia) antigens. The phenotype frequencies of class I and class II antigens showed high variability in their distribution among different areas, ranging from absence or presence in low frequency in one area to presence in about one-half of the mice in another area. The average phenotypic frequency of class I private antigens was 6.3%; at least 60% of class I alleles (blanks) could not be identified with the available reagents. The data suggest that there might be more than 100 alleles for each class I locus, H-2K and H-2D. The average phenotypic frequencies of Ia-1 private antigens was 10.8%. About 75% of Ia-1 alleles (blanks) could not be identified. The number of Ia-1 alleles was estimated to be in the range of 20 to 50. |
