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Publication : Expression of the LIM-homeodomain gene Lmx1a (dreher) during development of the mouse nervous system.

First Author  Failli V Year  2002
Journal  Mech Dev Volume  118
Issue  1-2 Pages  225-8
PubMed ID  12351192 Mgi Jnum  J:79521
Mgi Id  MGI:2388434 Doi  10.1016/s0925-4773(02)00254-x
Citation  Failli V, et al. (2002) Expression of the LIM-homeodomain gene Lmx1a (dreher) during development of the mouse nervous system. Mech Dev 118(1-2):225
abstractText  The expression pattern of Lmx1a, a LIM-homeodomain gene disrupted in the dreher mouse neurological mutant, is described during development. Lmx1a is predominantly expressed in the developing nervous system from embryonic day E8.5 to adulthood, in restricted areas. Major expression domains include the dorsal midline (roof plate) of the neural tube, the cortical hem, the otic vesicles, the developing cerebellum and the notochord. The Lmx1a expression pattern is therefore well correlated with the various aspects of the phenotype of the dreher mutant mice.
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