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Publication : P2X(3) receptor expression at early stage of mouse embryogenesis.

First Author  Boldogköi Z Year  2002
Journal  Mech Dev Volume  118
Issue  1-2 Pages  255-60
PubMed ID  12351197 Mgi Jnum  J:79527
Mgi Id  MGI:2388440 Doi  10.1016/s0925-4773(02)00280-0
Citation  Boldogkoi Z, et al. (2002) P2X(3) receptor expression at early stage of mouse embryogenesis. Mech Dev 118(1-2):255
abstractText  In this study we examined the expression of P2X(3) receptor in mouse embryos from E9.5 to E14.5 using immunohistochemistry. We found a uniform labeling in the developing trigeminal and dorsal root ganglia (DRG), while adult DRG and trigeminal ganglia expressed P2X(3) only in small-diameter neurons. In the brainstem, the mesencephalic trigeminal and facial motor nuclei were immunoreactive for P2X(3). P2X(3) was also transiently expressed in the developing brain, and precursors of spinal motor neurons. We also detected immunolabeling in the paravertebral sympathetic chain ganglia, in the sympathoadrenal cells and in non-neural tissues including testis, epidermis, wall of the aorta, as well as in subepidermal structures and mesenchymal tissues of limbs, branchial arches and tail.
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