First Author | Anderson TR | Year | 2002 |
Journal | Mech Dev | Volume | 114 |
Issue | 1-2 | Pages | 171-5 |
PubMed ID | 12175506 | Mgi Jnum | J:76822 |
Mgi Id | MGI:2180400 | Doi | 10.1016/s0925-4773(02)00051-5 |
Citation | Anderson TR, et al. (2002) Differential Pax6 promoter activity and transcript expression during forebrain development. Mech Dev 114(1-2):171-5 |
abstractText | Three different Pax6 promoters -- P0, P1, and P alpha -- show differential activity in the developing eye and spinal cord. To examine promoter usage during forebrain development, we performed in situ hybridization and reverse transcription-polymerase chain reaction to detect transcripts initiated from each promoter. Promoter-specific transcripts are expressed within subdomains of total Pax6 expression, but differ from one another in their spatial localization and expression over time. Additionally, we identified a novel P0-initiated transcript and detected a developmentally regulated antisense transcript. |