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Publication : Canine Bcl-xL gene and its expression in tumor cell lines.

First Author  Sano J Year  2003
Journal  J Vet Med Sci Volume  65
Issue  1 Pages  149-51
PubMed ID  12576724 Mgi Jnum  J:81952
Mgi Id  MGI:2450435 Doi  10.1292/jvms.65.149
Citation  Sano J, et al. (2003) Canine Bcl-xL Gene and Its Expression in Tumor Cell Lines. J Vet Med Sci 65(1):149-51
abstractText  The canine Bcl-xL gene was cloned and sequenced. Canine Bcl-xL cDNA clone was 1252 bp in length, and encoded 233 deduced amino acides. The predicted canine Bcl-xL amino acid sequence shared 99.6%, 97.0%, 97.9%, 98.7% and 98.3% homology with that of human, mouse, rat, sheep and pig Bcl-xL, respectively. RT-PCR analysis revealed that canine Bcl-xL mRNA was constitutively expressed in CL-1 (canine lymphoma) and GL-1 (canine B cell leukemia) cell lines.
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