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Publication : A new subgroup of the family 2 cystatins.

First Author  Cornwall GA Year  2003
Journal  Mol Cell Endocrinol Volume  200
Issue  1-2 Pages  1-8
PubMed ID  12644294 Mgi Jnum  J:82418
Mgi Id  MGI:2652963 Doi  10.1016/s0303-7207(02)00408-2
Citation  Cornwall GA, et al. (2003) A new subgroup of the family 2 cystatins. Mol Cell Endocrinol 200(1-2):1-8
abstractText  The cystatins are a superfamily of cysteine protease inhibitors. Several genes including Cres (cystatin-related epididymal spermatogenic), testatin, and cystatin T, have been identified that are related to the family 2 cystatins but lack critical consensus sites important for cysteine protease inhibition. In addition, these genes are primarily expressed in the reproductive tract suggesting they may have evolved to perform tissue-specific functions distinct from that of the typical cystatins. This review describes the CRES subgroup within the family 2 cystatins including potential new members and their putative functions in the reproductive tract.
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