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Publication : Analysis of the mouse transcriptome for genes involved in the function of the nervous system.

First Author  Gustincich S Year  2003
Journal  Genome Res Volume  13
Issue  6B Pages  1395-401
PubMed ID  12819138 Mgi Jnum  J:84170
Mgi Id  MGI:2665375 Doi  10.1101/gr.1135303
Citation  Gustincich S, et al. (2003) Analysis of the mouse transcriptome for genes involved in the function of the nervous system. Genome Res 13(6B):1395-401
abstractText  We analyzed the mouse Representative Transcript and Protein Set for molecules involved in brain function.We found full-length cDNAs of many known brain genes and discovered new members of known brain gene families, including Family 3 G-protein coupled receptors, voltage-gated channels, and connexins.We also identified previously unknown candidates for secreted neuroactive molecules.The existence of a large number of unique brain ESTs suggests an additional molecular complexity that remains to be explored.A list of genes containing CAG stretches in the coding region represents a first step in the potential identification of candidates for hereditary neurological disorders.
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