| First Author | Venkataraman K | Year | 2002 |
| Journal | FEBS Lett | Volume | 528 |
| Issue | 1-3 | Pages | 3-4 |
| PubMed ID | 12297269 | Mgi Jnum | J:86524 |
| Mgi Id | MGI:2680662 | Doi | 10.1016/s0014-5793(02)03248-9 |
| Citation | Venkataraman K, et al. (2002) Do longevity assurance genes containing Hox domains regulate cell development via ceramide synthesis?. FEBS Lett 528(1-3):3-4 |
| abstractText | A gene family containing a longevity assurance gene (Lag1p) motif is described. Database searches revealed >40 members of this family of transmembrane proteins, two of which have recently been shown to regulate the synthesis of ceramide, a lipid second messenger involved in a variety of cellular processes. We speculate that other family members, some of which contain a Hox domain, may also be involved in the synthesis of specific ceramide pools, perhaps explaining the role of longevity assurance genes in regulating development. |
