| First Author | Takebayashi S | Year | 2004 |
| Journal | Acta Otolaryngol Suppl | Issue | 551 |
| Pages | 18-21 | PubMed ID | 15078071 |
| Mgi Jnum | J:91339 | Mgi Id | MGI:3046499 |
| Doi | 10.1080/03655230310016753 | Citation | Takebayashi S, et al. (2004) Expression of beta-catenin in developing auditory epithelia of mice. Acta Otolaryngol Suppl (551):18-21 |
| abstractText | This study investigated the role of beta-catenin in the development of mouse auditory epithelia. Inner ears obtained from embryonic and newborn mice were used. Expression of beta-catenin was examined together with the marker for differentiated hair cells. In the early phase of development, intense expression of beta-catenin was found in auditory epithelia in which a number of Ki-67-positive cells were identified. Together with a decrease in proliferating cells, the intensity and area of beta-catenin expression were reduced. In addition, during differentiation and maturation of hair cells, the area of beta-catenin expression was further limited. These findings suggest that patterns of expression of beta-catenin are closely linked with the status of auditory epithelia development. |
