| First Author | Mowen KA | Year | 2004 |
| Journal | Immunol Rev | Volume | 202 |
| Pages | 203-22 | PubMed ID | 15546395 |
| Mgi Jnum | J:95555 | Mgi Id | MGI:3526503 |
| Doi | 10.1111/j.0105-2896.2004.00209.x | Citation | Mowen KA, et al. (2004) Signaling pathways in Th2 development. Immunol Rev 202:203-22 |
| abstractText | In order for an immune response to be successful, it must be of the appropriate type and magnitude. Intracellular residing pathogens require a cell-mediated immune response, whereas extracellular pathogens evoke a humoral immune response. T-helper (Th) cells orchestrate the immune response and are divided into two subsets, Th1 and Th2 cells. Here, we discuss the mechanisms of Th2 development with a focus on signal transduction pathways that influence Th2 differentiation. |
