| First Author | Inazu T | Year | 2005 |
| Journal | Mol Biol Rep | Volume | 32 |
| Issue | 1 | Pages | 35-40 |
| PubMed ID | 15865208 | Mgi Jnum | J:99487 |
| Mgi Id | MGI:3582749 | Doi | 10.1007/s11033-004-4747-x |
| Citation | Inazu T, et al. (2005) Cloning, expression and chromosomal assignment of human pleckstrin 2. Mol Biol Rep 32(1):35-40 |
| abstractText | We report the isolation of human pleckstrin 2 cDNA. The cDNA contains a 1059 bp open reading frame encoding a polypeptide of 353 amino acid residues. The deduced amino acid sequence indicates that pleckstrin 2 contains two pleckstrin homology domains and a DEP (dishvelled, egl-10, and pleckstrin) domain and had a 95% identity with the sequence of mouse pleckstrin 2. Northern blot and a reverse transcription-coupled polymerase chain reaction analysis revealed that pleckstrin 2 mRNA is widely expressed in a variety of cell lines. The chromosomal location of the mouse pleckstrin 2 gene was on the D3 band of chromosome 12, as determined by fluorescence in situ hybridization and the human pleckstrin 2 gene was mapped to chromosome 14q24.1 by a bioinformatics analysis. |
