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Publication : A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases.

First Author  Hunt MC Year  2005
Journal  J Lipid Res Volume  46
Issue  9 Pages  2029-32
PubMed ID  16103133 Mgi Jnum  J:100465
Mgi Id  MGI:3588599 Doi  10.1194/jlr.E500003-JLR200
Citation  Hunt MC, et al. (2005) A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases. J Lipid Res 46(9):2029-32
abstractText  Acyl-CoA thioesterases, also known as acyl-CoA hydrolases, are a group of enzymes that hydrolyze CoA esters such as acyl-CoAs (saturated, unsaturated, branched-chain), bile acid-CoAs, CoA esters of prostaglandins, etc., to the corresponding free acid and CoA. However, there is significant confusion regarding the nomenclature of these genes. In agreement with the HUGO Gene Nomenclature Committee and the Mouse Genomic Nomenclature Committee, a revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases has been suggested for the 12 member family. The family root symbol is ACOT, with human genes named ACOT1-ACOT12, and rat and mouse genes named Acot1-Acot12. Several of the ACOT genes are the result of splicing events, and these splice variants are cataloged.
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