First Author | Venkitaraman AR | Year | 2001 |
Journal | Curr Opin Cell Biol | Volume | 13 |
Issue | 3 | Pages | 338-43 |
PubMed ID | 11343905 | Mgi Jnum | J:114055 |
Mgi Id | MGI:3688065 | Doi | 10.1016/s0955-0674(00)00217-9 |
Citation | Venkitaraman AR (2001) Chromosome stability, DNA recombination and the BRCA2 tumour suppressor. Curr Opin Cell Biol 13(3):338-43 |
abstractText | The BRCA2 tumour suppressor works in DNA recombination and repair pathways to preserve genome integrity. Recent progress provides fresh insights into its role as a regulator of the Rad51 recombination protein, underpinning a model in which BRCA2's involvement in chromosome stability and tumour suppression arises from its participation in recombinational processes essential for DNA replication. |