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Publication : Chromosome stability, DNA recombination and the BRCA2 tumour suppressor.

First Author  Venkitaraman AR Year  2001
Journal  Curr Opin Cell Biol Volume  13
Issue  3 Pages  338-43
PubMed ID  11343905 Mgi Jnum  J:114055
Mgi Id  MGI:3688065 Doi  10.1016/s0955-0674(00)00217-9
Citation  Venkitaraman AR (2001) Chromosome stability, DNA recombination and the BRCA2 tumour suppressor. Curr Opin Cell Biol 13(3):338-43
abstractText  The BRCA2 tumour suppressor works in DNA recombination and repair pathways to preserve genome integrity. Recent progress provides fresh insights into its role as a regulator of the Rad51 recombination protein, underpinning a model in which BRCA2's involvement in chromosome stability and tumour suppression arises from its participation in recombinational processes essential for DNA replication.
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