First Author | Chapman VM | Year | 1972 |
Journal | Genetics | Volume | 70 |
Issue | 2 | Pages | 299-305 |
PubMed ID | 17248564 | Mgi Jnum | J:4415 |
Mgi Id | MGI:52908 | Doi | 10.1093/genetics/70.2.299 |
Citation | Chapman VM, et al. (1972) Glutamate Oxaloacetate Transaminase (Got) Genetics in the Mouse: Polymorphism of Got-1. Genetics 70(2):299-305 |
abstractText | We have examined a polymorphism for the soluble glutamate oxaloacetate (GOT-1) isozyme system which was found in the Asian mouse Mus castaneus. Variants of GOT-1 segregate as though they are controlled by codominant alleles for a single autosomal locus which we have designated Got-1. No close linkage of genes for soluble and mitochondrial forms of the enzyme, GOT-1 and GOT-2 respectively, was observed. Furthermore, no close linkage of Got-1 and the loci c, Gpi-1, Mod-2, Mod-1, Ld-1, Gpd-1, Pgm-1 or Gpo-1 was observed. Our results demonstrate the utility of sampling Mus from diverse populations to extend the repertoire of polymorphic loci and the genetic linkage map. |