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Publication : Advances in polycystic kidney disease.

First Author  Schneider MC Year  1996
Journal  Mol Med Today Volume  2
Issue  2 Pages  70-5
PubMed ID  8796859 Mgi Jnum  J:31908
Mgi Id  MGI:79413 Doi  10.1016/1357-4310(96)88741-7
Citation  Schneider MC (1996) Advances in polycystic kidney disease. Mol Med Today 2(2):70-5
abstractText  Until recently, the nature of the molecules involved in inherited cystic disease of the kidney remained unknown. These diseases are characterized by the development of multiple abnormal fluid-filled sacs or dilations in the kidney parenchyma, often leading to significant renal failure. The recent characterization of the PKD1 gene product and of other genes involved in murine polycystic models underscores the complexity of the pathways that lead to renal cystic disease.
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