| First Author | Sun B | Year | 2007 |
| Journal | FEBS Lett | Volume | 581 |
| Issue | 17 | Pages | 3277-82 |
| PubMed ID | 17597618 | Mgi Jnum | J:123731 |
| Mgi Id | MGI:3719339 | Doi | 10.1016/j.febslet.2007.06.021 |
| Citation | Sun B, et al. (2007) Clusterin is associated with spontaneous breast cancer in TA2 mice. FEBS Lett 581(17):3277-82 |
| abstractText | Two-dimensional electrophoresis and Matrix-assisted laser desorption ionization-time of flight-time of mass spectrometry were used to detect the differentially expressed proteins in serum of tientsin albinao 2 mice with spontaneous breast cancer, normal tientsin albinao 2 mice and tientsin albinao 1 mice. Only nuclear clusterin (n-CLU) was expressed in tientsin albinao 1. Immunohistochemistry and western blot validated that n-CLU was present in normal tientsin albinao 2 and tientsin albinao 1 mammary epithelium, and secretory clusterin expressed in the cytoplasm of normal tientsin albinao 2 mammary epithelium and spontaneous breast cancer. n-CLU may play an important role in tientsin albinao 2 spontaneous breast cancer initiation and development. |
