| First Author | Park JL | Year | 2004 |
| Journal | Eur J Pharmacol | Volume | 496 |
| Issue | 1-3 | Pages | 213-4 |
| PubMed ID | 15288593 | Mgi Jnum | J:134628 |
| Mgi Id | MGI:3789426 | Doi | 10.1016/j.ejphar.2004.06.022 |
| Citation | Park JL, et al. (2004) GLUT1-deficient mice exhibit impaired endothelium-dependent vascular relaxation. Eur J Pharmacol 496(1-3):213-4 |
| abstractText | We tested the hypothesis that decreased glucose transporter 1 (GLUT1) expression alters endothelial function. Nitric oxide-dependent endothelial relaxation, but not endothelium-independent relaxation, was significantly reduced in aortas from transgenic mice expressing GLUT1 antisense mRNA, compared to aortas from nontransgenic littermates. These data suggest that GLUT1-dependent glucose metabolism may play an important role in regulating endothelial function. |
