| First Author | Makarova A | Year | 2008 |
| Journal | Neurosci Lett | Volume | 442 |
| Issue | 2 | Pages | 91-5 |
| PubMed ID | 18602448 | Mgi Jnum | J:138201 |
| Mgi Id | MGI:3804558 | Doi | 10.1016/j.neulet.2008.06.070 |
| Citation | Makarova A, et al. (2008) The LDL receptor-related protein can form homo-dimers in neuronal cells. Neurosci Lett 442(2):91-5 |
| abstractText | The ability of the low density lipoprotein receptor-related protein (LRP) to form homo-dimers was studied in mouse neuroblastoma and human neuroglioma cells as well as in primary cortical cultures from adult mouse brain. Homo-dimerization of LRP light chain (LC) was shown by several methods including co-immunoprecipitation, fluorescence lifetime imaging microscopy, and bimolecular fluorescence complementation assay. The requirement of intact NPXY motifs of LRP LC for homo-dimerization was ruled out by co-immunoprecipitation assay. |
