|  Help  |  About  |  Contact Us

Publication : SSAO/VAP-1 protein expression during mouse embryonic development.

First Author  Valente T Year  2008
Journal  Dev Dyn Volume  237
Issue  9 Pages  2585-93
PubMed ID  18729210 Mgi Jnum  J:138804
Mgi Id  MGI:3806413 Doi  10.1002/dvdy.21682
Citation  Valente T, et al. (2008) SSAO/VAP-1 protein expression during mouse embryonic development. Dev Dyn 237(9):2585-93
abstractText  SSAO/VAP-1 is a multifunctional enzyme depending on in which tissue it is expressed. SSAO/VAP-1 is present in almost all adult mammalian tissues, especially in highly vascularised ones and in adipocytes. SSAO/VAP-1 is an amine oxidase able to metabolise various endogenous or exogenous primary amines. Its catalytic activity can lead to cellular oxidative stress, which has been implicated in several pathologies (atherosclerosis, diabetes, and Alzheimer's disease). The aim of this work is to achieve a study of SSAO/VAP-1 protein expression during mouse embryogenesis. Our results show that SSAO/VAP-1 appears early in the development of the vascular system, adipose tissue, and smooth muscle cells. Moreover, its expression is strong in several epithelia of the sensory organs, as well as in the development of cartilage sites. Altogether, this suggests that SSAO/VAP-1 enzyme could be involved in the differentiation processes that take place during embryonic development, concretely in tissue vascularisation. Developmental Dynamics 237:2585-2593, 2008. (c) 2008 Wiley-Liss, Inc.
Quick Links:
 
Quick Links:
 

Expression

Publication --> Expression annotations

 

Other

3 Authors

5 Bio Entities

Trail: Publication

121 Expression

Trail: Publication