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Publication : It's a free for all--insulin-positive cells join the group of potential progenitors for pancreatic ductal adenocarcinoma.

First Author  Morris JP 4th Year  2009
Journal  Cancer Cell Volume  16
Issue  5 Pages  359-61
PubMed ID  19878864 Mgi Jnum  J:153950
Mgi Id  MGI:4366643 Doi  10.1016/j.ccr.2009.10.006
Citation  Morris JP 4th, et al. (2009) It's a free for all--insulin-positive cells join the group of potential progenitors for pancreatic ductal adenocarcinoma. Cancer Cell 16(5):359-61
abstractText  Despite significant efforts, the cellular compartment that gives rise to pancreatic ductal adenocarcinoma (PDAC), one of the most lethal human cancers, remains obscure. In this issue of Cancer Cell, Gidekel Friedlander and colleagues demonstrate that under conditions of tissue damage, mutant Kras can drive previously unsuspected insulin-positive endocrine cells into PDA.
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