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Publication : The Collaborative Cross, a community resource for the genetic analysis of complex traits.

First Author  Churchill GA Year  2004
Journal  Nat Genet Volume  36
Issue  11 Pages  1133-7
PubMed ID  15514660 Mgi Jnum  J:155045
Mgi Id  MGI:4412184 Doi  10.1038/ng1104-1133
Citation  Churchill GA, et al. (2004) The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet 36(11):1133-7
abstractText  The goal of the Complex Trait Consortium is to promote the development of resources that can be used to understand, treat and ultimately prevent pervasive human diseases. Existing and proposed mouse resources that are optimized to study the actions of isolated genetic loci on a fixed background are less effective for studying intact polygenic networks and interactions among genes, environments, pathogens and other factors. The Collaborative Cross will provide a common reference panel specifically designed for the integrative analysis of complex systems and will change the way we approach human health and disease.
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